By Robert Preidt


HealthDay Reporter


WEDNESDAY, Oct. 10, 2018 (HealthDay News) — A 13-year-old lady who has been with out hair on her scalp because the age of two has observed vital regrowth ever since taking a drug supposed to lend a hand ease her eczema, docs say.

Dr. Maryanne Makredes Senna of Massachusetts General Hospital and her colleagues within the division of dermatology had been “quite surprised” on the lady’s hair regrowth, as a result of “other treatments that can helpwith hair loss did not in her case.”

The unnamed lady has alopecia totalis — a complete loss of scalp hair — at the side of eczema, and was once receiving weekly injections of the drug dupilumab (logo identify Dupixent) to regard her eczema.

After six weeks of remedy, very high-quality hairs began appearing at the lady’s scalp, and by way of seven months of remedy she had vital hair regrowth, in line with the case find out about printed Oct. 10 in JAMA Dermatology.

“As far as we know, this is the first report of hair regrowth with dupilumab in a patient with any degree of alopecia areata,” Senna stated in a clinic information unlock.

The hair expansion turns out tied to the drug. According to the docs, when the woman needed to prevent taking dupilumab for 2 months because of a transformation in her insurance plans, her newly regrown hair began to fall out. But when she began the drug remedy once more, the hair expansion resumed.

It’s no longer transparent how the drug is having this impact. But Senna defined that dupilumab objectives an immune gadget pathway identified to be overactive in eczema. Recent research have prompt the similar pathway might induce autoimmune-caused hair loss.

“Right now, it’s hard to know whether dupilumab could induce hair growth in other alopecia patients, but I suspect it may be helpful in patients with extensive active eczema and active alopecia areata,” stated Senna, who’s primary investigator of the Hair Academic Innovative Research (HAIR) unit on the Boston clinic.

“We’ve submitted a proposal for a clinical trial using dupilumab in this patient population and hope to be able to investigate it further in the near future,” Senna stated.

One dermatologist who was once unconnected to the case stated the consequences are intriguing, however initial.

“More research is needed to show if this drug or other biologics will grow hair,” stated Dr. Michele Green, who practices at Lenox Hill Hospital in New York City. “It is possible that this immune mechanism may be the key to treating patients with alopecia areata and unlocking the treatment for this mysterious autoimmune disease.”



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Sources

SOURCES:  Michele S. Green, M.D., dermatologist, Lenox Hill Hospital, New York City; Massachusetts General Hospital, information unlock, Oct. 10, 2018




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